The Last Man is an apocalyptic, dystopian science fiction novel by Mary Shelley, first published in 1826. The narrative concerns Europe in the late 21st century, ravaged by a mysterious pandemic illness that rapidly sweeps across the entire globe, ultimately resulting in the near-extinction of humanity. It also includes discussion of the British state as a republic, for which Shelley sat in meetings of the House of Commons to gain insight to the governmental system of the Romantic era. The novel includes many fictive allusions to her husband Percy Bysshe Shelley, who drowned in a shipwreck four years before the book's publication, as well as their close friend Lord Byron, who had died two years previously.

The Last Man was critically savaged and remained largely obscure at the time of its publication. It was not until the 1960s that the novel resurfaced for the public as a work of fiction, not prophecy. The Last Man is one of the first pieces of dystopian fiction published.